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Key Highlights: The LIGHTUP Anti Aging Serum Dark Spots Corrector is a powerful formula that helps to reduce the signs of aging while correcting dark spots on the skin
For experiments, we used 8-week or older male and female C57BL/6J mice, Glp1r-IRES-Cre mice (Glp1rtm1.1(cre)Lbrl/RcngJ, strain 029283, RRID: IMSR_JAX:029283), Glp1r-IRES-Cre mice crossed to the Ai14 tdTomato reporter line (B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J, strain 007914, RRID: IMSR_JAX:007914), Glp1r flox/flox mice (B6(SJL)-Glp1rtm1.1Stof/J, strain 035238, RRID: IMSR_JAX:035238), Dat-Cre mice (B6.SJL-Slc6a3tm1.1(cre)Bkmn/J, strain 006660, RRID: IMSR_JAX:006660) Gcg-Cre mice (C57BL/6J-Tg(Gcg-cre)-1Mmsc/Mmmh, stock 051056-MU, RRID: MMRRC_051056-MU) and Glp1r S33W mice (described below)
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